Hyperactivated PTP1B phosphatase in parvalbumin neurons alters anterior cingulate inhibitory circuits and induces autism-like behaviors

Individuals with autism spectrum disorder (ASD) have social interaction deficits and difficulty filtering information. Inhibitory interneurons filter information at pyramidal neurons of the anterior cingulate cortex (ACC), an integration hub for higher-order thalamic inputs important for social inte...

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Detalles Bibliográficos
Autores principales: Zhang, Li, Qin, Zhaohong, Ricke, Konrad M., Cruz, Shelly A., Stewart, Alexandre F. R., Chen, Hsiao-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039907/
https://www.ncbi.nlm.nih.gov/pubmed/32094367
http://dx.doi.org/10.1038/s41467-020-14813-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039907/
https://www.ncbi.nlm.nih.gov/pubmed/32094367
http://dx.doi.org/10.1038/s41467-020-14813-z

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