Cargando…
Hyperactivated PTP1B phosphatase in parvalbumin neurons alters anterior cingulate inhibitory circuits and induces autism-like behaviors
Individuals with autism spectrum disorder (ASD) have social interaction deficits and difficulty filtering information. Inhibitory interneurons filter information at pyramidal neurons of the anterior cingulate cortex (ACC), an integration hub for higher-order thalamic inputs important for social inte...
Autores principales: | Zhang, Li, Qin, Zhaohong, Ricke, Konrad M., Cruz, Shelly A., Stewart, Alexandre F. R., Chen, Hsiao-Huei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039907/ https://www.ncbi.nlm.nih.gov/pubmed/32094367 http://dx.doi.org/10.1038/s41467-020-14813-z |
Ejemplares similares
-
Activation of tyrosine phosphatase PTP1B in pyramidal neurons impairs endocannabinoid signaling by tyrosine receptor kinase trkB and causes schizophrenia-like behaviors in mice
por: Qin, Zhaohong, et al.
Publicado: (2020) -
Neuronal protein-tyrosine phosphatase 1B hinders sensory-motor functional recovery and causes affective disorders in two different focal ischemic stroke models
por: Cruz, Shelly A., et al.
Publicado: (2020) -
Diversity of inhibitory and excitatory parvalbumin interneuron circuits in the dorsal horn
por: Gradwell, Mark A., et al.
Publicado: (2022) -
Loss of Dopamine D2 Receptors Increases Parvalbumin-Positive
Interneurons in the Anterior Cingulate Cortex
por: Graham, Devon L., et al.
Publicado: (2014) -
Myelination of parvalbumin interneurons shapes the function of cortical sensory inhibitory circuits
por: Benamer, Najate, et al.
Publicado: (2020)