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Adaption of the ex vivo mycobacterial growth inhibition assay for use with murine lung cells

In the absence of a correlate(s) of protection against human tuberculosis and a validated animal model of the disease, tools to facilitate vaccine development must be identified. We present an optimised ex vivo mycobacterial growth inhibition assay (MGIA) to assess the ability of host cells within t...

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Detalles Bibliográficos
Autores principales: Painter, Hannah, Prabowo, Satria A., Cia, Felipe, Stockdale, Lisa, Tanner, Rachel, Willcocks, Samuel, Reljic, Rajko, Fletcher, Helen A., Zelmer, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039920/
https://www.ncbi.nlm.nih.gov/pubmed/32094451
http://dx.doi.org/10.1038/s41598-020-60223-y