Development of Relaxin-3 Agonists and Antagonists Based on Grafted Disulfide-Stabilized Scaffolds

Relaxin-3 is a neuropeptide with important roles in metabolism, arousal, learning and memory. Its cognate receptor is the relaxin family peptide-3 (RXFP3) receptor. Relaxin-3 agonist and antagonist analogs have been shown to be able to modulate food intake in rodent models. The relaxin-3 B-chain is...

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Detalles Bibliográficos
Autores principales: Lee, Han Siean, Postan, Michael, Song, Angela, Clark, Richard J., Bathgate, Ross A. D., Haugaard-Kedström, Linda M., Rosengren, K. Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039932/
https://www.ncbi.nlm.nih.gov/pubmed/32133341
http://dx.doi.org/10.3389/fchem.2020.00087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039932/
https://www.ncbi.nlm.nih.gov/pubmed/32133341
http://dx.doi.org/10.3389/fchem.2020.00087

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