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Crystalline Silica Impairs Efferocytosis Abilities of Human and Mouse Macrophages: Implication for Silica-Associated Systemic Sclerosis

Inhalation of crystalline silica (SiO(2)) is a risk factor of systemic autoimmune diseases such as systemic sclerosis (SSc) and fibrotic pulmonary disorders such as silicosis. A defect of apoptotic cell clearance (i.e., efferocytosis, a key process in the resolution of inflammation) is reported in m...

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Detalles Bibliográficos
Autores principales: Lescoat, Alain, Ballerie, Alice, Lelong, Marie, Augagneur, Yu, Morzadec, Claudie, Jouneau, Stéphane, Jégo, Patrick, Fardel, Olivier, Vernhet, Laurent, Lecureur, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039938/
https://www.ncbi.nlm.nih.gov/pubmed/32133004
http://dx.doi.org/10.3389/fimmu.2020.00219