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Development of Potent Forchlorfenuron Analogs and Their Cytotoxic Effect in Cancer Cell Lines

Forchlorfenuron (FCF) is a synthetic plant cytokinin widely used in agriculture to promote fruit size, that paradoxically inhibits proliferation, migration, and invasion in human cancer cell lines. FCF has also been shown to affect HIF-1α and HER2, which are both known to play a crucial role in canc...

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Detalles Bibliográficos
Autores principales: Kim, Kyu Kwang, Singh, Rakesh K., Khazan, Negar, Kodza, Arif, Singh, Niloy A., Jones, Aaron, Sivagnanalingam, Umayal, Towner, Mary, Itamochi, Hiroaki, Turner, Rachael, Moore, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039965/
https://www.ncbi.nlm.nih.gov/pubmed/32094384
http://dx.doi.org/10.1038/s41598-020-59824-4