Droplet-based digital antibiotic susceptibility screen reveals single-cell clonal heteroresistance in an isogenic bacterial population

Since antibiotic resistance is a major threat to global health, recent observations that the traditional test of minimum inhibitory concentration (MIC) is not informative enough to guide effective antibiotic treatment are alarming. Bacterial heteroresistance, in which seemingly susceptible isogenic...

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Detalles Bibliográficos
Autores principales: Scheler, Ott, Makuch, Karol, Debski, Pawel R., Horka, Michal, Ruszczak, Artur, Pacocha, Natalia, Sozański, Krzysztof, Smolander, Olli-Pekka, Postek, Witold, Garstecki, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039976/
https://www.ncbi.nlm.nih.gov/pubmed/32094499
http://dx.doi.org/10.1038/s41598-020-60381-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039976/
https://www.ncbi.nlm.nih.gov/pubmed/32094499
http://dx.doi.org/10.1038/s41598-020-60381-z

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