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New insight into podocyte slit diaphragm, a therapeutic target of proteinuria

Dysfunction of slit diaphragm, a cell–cell junction of glomerular podocytes, is involved in the development of proteinuria in several glomerular diseases. Slit diaphragm should be a target of a novel therapy for proteinuria. Nephrin, NEPH1, P-cadherin, FAT, and ephrin-B1 were reported to be extracel...

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Detalles Bibliográficos
Autores principales: Kawachi, Hiroshi, Fukusumi, Yoshiyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040068/
https://www.ncbi.nlm.nih.gov/pubmed/32020343
http://dx.doi.org/10.1007/s10157-020-01854-3