Anthralin Suppresses the Proliferation of Influenza Virus by Inhibiting the Cap-Binding and Endonuclease Activity of Viral RNA Polymerase

Influenza virus RNA-dependent RNA polymerase (vRdRp) does not have capping activity and relies on the capped RNAs produced by the host RNA polymerase II (RNAPII). The viral polymerases process the capped RNAs to produce short capped RNA fragments that are used as primers to initiate the transcriptio...

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Detalles Bibliográficos
Autores principales: Hu, Ao, Li, Jing, Tang, Wei, Liu, Ge, Zhang, Haiwei, Liu, Chunlan, Chen, Xulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040080/
https://www.ncbi.nlm.nih.gov/pubmed/32132985
http://dx.doi.org/10.3389/fmicb.2020.00178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040080/
https://www.ncbi.nlm.nih.gov/pubmed/32132985
http://dx.doi.org/10.3389/fmicb.2020.00178

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