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Comparison of the gamma-Pareto convolution with conventional methods of characterising metformin pharmacokinetics in dogs
A model was developed for long term metformin tissue retention based upon temporally inclusive models of serum/plasma concentration ([Formula: see text] ) having power function tails called the gamma-Pareto type I convolution (GPC) model and was contrasted with biexponential (E2) and noncompartmenta...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040082/ https://www.ncbi.nlm.nih.gov/pubmed/31865474 http://dx.doi.org/10.1007/s10928-019-09666-z |