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Comparison of the gamma-Pareto convolution with conventional methods of characterising metformin pharmacokinetics in dogs

A model was developed for long term metformin tissue retention based upon temporally inclusive models of serum/plasma concentration ([Formula: see text] ) having power function tails called the gamma-Pareto type I convolution (GPC) model and was contrasted with biexponential (E2) and noncompartmenta...

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Detalles Bibliográficos
Autores principales: Wesolowski, Carl A., Wanasundara, Surajith N., Babyn, Paul S., Alcorn, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040082/
https://www.ncbi.nlm.nih.gov/pubmed/31865474
http://dx.doi.org/10.1007/s10928-019-09666-z