Thermodynamic, Spatial and Methodological Considerations for the Manufacturing of Therapeutic Polymer Nanoparticles

PURPOSE: Evaluate fundamental parameters that dictate the effectiveness of drug loading. METHODS: A model water-soluble drug lacking ionizable groups, pirfenidone (PFD), was encapsulated through nanoprecipitation in poly(ethylene glycol)-poly(lactic acid) (PEG-PLA)-poly(lactic-co-glycolic acid) (PLG...

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Detalles Bibliográficos
Autores principales: Maslanka Figueroa, Sara, Fleischmann, Daniel, Beck, Sebastian, Goepferich, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040083/
https://www.ncbi.nlm.nih.gov/pubmed/32095934
http://dx.doi.org/10.1007/s11095-020-2783-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040083/
https://www.ncbi.nlm.nih.gov/pubmed/32095934
http://dx.doi.org/10.1007/s11095-020-2783-4

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