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Theory and applications of differential scanning fluorimetry in early-stage drug discovery

Differential scanning fluorimetry (DSF) is an accessible, rapid, and economical biophysical technique that has seen many applications over the years, ranging from protein folding state detection to the identification of ligands that bind to the target protein. In this review, we discuss the theory,...

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Detalles Bibliográficos
Autores principales: Gao, Kai, Oerlemans, Rick, Groves, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040159/
https://www.ncbi.nlm.nih.gov/pubmed/32006251
http://dx.doi.org/10.1007/s12551-020-00619-2