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Antiangiogeneic Strategies in Mesothelioma

There is a strong rationale for inhibiting angiogenesis in mesothelioma. Vascular endothelial growth factor (VEGF) is an autocrine growth factor in mesothelioma and a potent mitogen for mesothelial cells. Further, the abnormal tumor vasculature promotes raised interstitial pressure and hypoxia, whic...

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Detalles Bibliográficos
Autores principales: Nowak, Anna K., Brosseau, Solenn, Cook, Alistair, Zalcman, Gérard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040194/
https://www.ncbi.nlm.nih.gov/pubmed/32133285
http://dx.doi.org/10.3389/fonc.2020.00126