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Classical Activation of Macrophages Leads to Lipid Droplet Formation Without de novo Fatty Acid Synthesis

Altered lipid metabolism in macrophages is associated with various important inflammatory conditions. Although lipid metabolism is an important target for therapeutic intervention, the metabolic requirement involved in lipid accumulation during pro-inflammatory activation of macrophages remains inco...

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Detalles Bibliográficos
Autores principales: Rosas-Ballina, Mauricio, Guan, Xue Li, Schmidt, Alexander, Bumann, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040478/
https://www.ncbi.nlm.nih.gov/pubmed/32132994
http://dx.doi.org/10.3389/fimmu.2020.00131