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The Release of the Bromodomain Ligand N,N-Dimethylacetamide Adds Bioactivity to a Resorbable Guided Bone Regeneration Membrane in a Rabbit Calvarial Defect Model

N,N-Dimethylacetamide (DMA) is FDA approved as an excipient and is used as drug-delivery vehicle. Due to its amphipathic nature and diverse bioactivities, it appears to be a good combination of biodegradable poly-lactide-co-glycolide (PLGA)-based guided bone regeneration membranes. Here we show that...

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Detalles Bibliográficos
Autores principales: Siegenthaler, Barbara, Ghayor, Chafik, Ruangsawasdi, Nisarat, Weber, Franz E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040842/
https://www.ncbi.nlm.nih.gov/pubmed/31973011
http://dx.doi.org/10.3390/ma13030501