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Overexpression of microRNA-185 alleviates intervertebral disc degeneration through inactivation of the Wnt/β-catenin signaling pathway and downregulation of Galectin-3

BACKGROUND: Recent studies have found that microRNAs (miRNAs) play a critical role in development and progression of intervertebral disc degeneration. In the present study, we examined the role of miR-185 in nucleus pulposus cell behavior in vitro and the histological changes of intervertebral disc...

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Detalles Bibliográficos
Autores principales: Yun, Zhennan, Wang, Yuhang, Feng, Wei, Zang, Junting, Zhang, Daguang, Gao, Yuhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040930/
https://www.ncbi.nlm.nih.gov/pubmed/32090685
http://dx.doi.org/10.1177/1744806920902559