Cargando…
Overexpression of microRNA-185 alleviates intervertebral disc degeneration through inactivation of the Wnt/β-catenin signaling pathway and downregulation of Galectin-3
BACKGROUND: Recent studies have found that microRNAs (miRNAs) play a critical role in development and progression of intervertebral disc degeneration. In the present study, we examined the role of miR-185 in nucleus pulposus cell behavior in vitro and the histological changes of intervertebral disc...
Autores principales: | Yun, Zhennan, Wang, Yuhang, Feng, Wei, Zang, Junting, Zhang, Daguang, Gao, Yuhang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040930/ https://www.ncbi.nlm.nih.gov/pubmed/32090685 http://dx.doi.org/10.1177/1744806920902559 |
Ejemplares similares
-
Degeneration of the intervertebral disc
por: Urban, Jill PG, et al.
Publicado: (2003) -
In-Vivo Nucleus Pulposus-Specific Regulation of Adult Murine Intervertebral Disc Degeneration via Wnt/Beta-Catenin Signaling
por: Holguin, Nilsson, et al.
Publicado: (2018) -
p300 arrests intervertebral disc degeneration by regulating the FOXO3/Sirt1/Wnt/β‐catenin axis
por: Hao, Yingjie, et al.
Publicado: (2022) -
Oestrogen and parathyroid hormone alleviate lumbar intervertebral disc degeneration in ovariectomized rats and enhance Wnt/β-catenin pathway activity
por: Jia, Haobo, et al.
Publicado: (2016) -
Circular RNA ITCH promotes extracellular matrix degradation via activating Wnt/β-catenin signaling in intervertebral disc degeneration
por: Zhang, Feng, et al.
Publicado: (2021)