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Comparison of suspension MDCK cells, adherent MDCK cells, and LLC‐MK2 cells for selective isolation of influenza viruses to be used as vaccine seeds

BACKGROUND: Cell‐based influenza vaccines can solve the problem of the frequent occurrence of egg adaptation–associated antigenic changes observed in egg‐based vaccines. Seed viruses for cell‐based vaccines can be prepared from clinical specimens by cell culture; however, clinical samples risk harbo...

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Detalles Bibliográficos
Autores principales: Harada, Yuichi, Takahashi, Hitoshi, Trusheim, Heidi, Roth, Bernhard, Mizuta, Katsumi, Hirata‐Saito, Asumi, Ogane, Teruko, Odagiri, Takato, Tashiro, Masato, Yamamoto, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040968/
https://www.ncbi.nlm.nih.gov/pubmed/31651085
http://dx.doi.org/10.1111/irv.12694