Astroglial TLR9 antagonism promotes chemotaxis and alternative activation of macrophages via modulation of astrocyte-derived signals: implications for spinal cord injury

BACKGROUND: The recruitment of immune system cells into the central nervous system (CNS) has a profound effect on the outcomes of injury and disease. Glia-derived chemoattractants, including chemokines, play a pivotal role in this process. In addition, cytokines and chemokines influence the phenotyp...

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Detalles Bibliográficos
Autores principales: Li, Lun, Ni, Li, Heary, Robert F., Elkabes, Stella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041103/
https://www.ncbi.nlm.nih.gov/pubmed/32098620
http://dx.doi.org/10.1186/s12974-020-01748-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041103/
https://www.ncbi.nlm.nih.gov/pubmed/32098620
http://dx.doi.org/10.1186/s12974-020-01748-x

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