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DNA aneuploidy and tissue architecture in oral potentially malignant disorders with epithelial dysplasia assessed by a 10 locus FISH panel

Subjectivity in oral dysplasia grading has prompted evaluation of molecular-based tests to predict malignant transformation. Aneuploidy detected by DNA image-based cytometry (ICM) is currently the best predictor but fails to detect certain high risk lesions. A novel multiplex fluorescence in situ hy...

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Detalles Bibliográficos
Autores principales: Zaini, Zuraiza Mohamad, Neat, Michael, Stokes, Angela, Tavassoli, Mahvash, Odell, Edward W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041104/
https://www.ncbi.nlm.nih.gov/pubmed/32020221
http://dx.doi.org/10.3892/or.2020.7461