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Comparison of the efficacy and safety of tacrolimus monotherapy and cyclophosphamide combined with glucocorticoid in the treatment of adult primary membranous nephropathy: protocol of a multicenter, randomized, controlled, open study

BACKGROUND: Idiopathic membranous nephropathy (IMN) remains the leading cause of adult nephrotic syndrome. Immunosuppressive therapy with cyclophosphamide (CTX) is often successful in reducing proteinuria, but its use is associated with severe side effects. Tacrolimus (TAC) is effective in achieving...

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Detalles Bibliográficos
Autores principales: Chen, Shasha, Ren, Song, Wang, Amanda Y., Tran, Hieu, Li, Zheng, Cheng, Xiaoyun, Liu, Manli, Li, Guisen, Wang, Li, Hong, Daqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041116/
https://www.ncbi.nlm.nih.gov/pubmed/32093742
http://dx.doi.org/10.1186/s13063-020-4144-3