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Assessing stationary distributions derived from chromatin contact maps

BACKGROUND: The spatial configuration of chromosomes is essential to various cellular processes, notably gene regulation, while architecture related alterations, such as translocations and gene fusions, are often cancer drivers. Thus, eliciting chromatin conformation is important, yet challenging du...

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Detalles Bibliográficos
Autores principales: Segal, Mark R., Fletez-Brant, Kipper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041182/
https://www.ncbi.nlm.nih.gov/pubmed/32093610
http://dx.doi.org/10.1186/s12859-020-3424-y