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Assessing stationary distributions derived from chromatin contact maps
BACKGROUND: The spatial configuration of chromosomes is essential to various cellular processes, notably gene regulation, while architecture related alterations, such as translocations and gene fusions, are often cancer drivers. Thus, eliciting chromatin conformation is important, yet challenging du...
Autores principales: | Segal, Mark R., Fletez-Brant, Kipper |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041182/ https://www.ncbi.nlm.nih.gov/pubmed/32093610 http://dx.doi.org/10.1186/s12859-020-3424-y |
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