Cargando…

MOMO - multi-objective metabolic mixed integer optimization: application to yeast strain engineering

BACKGROUND: In this paper, we explore the concept of multi-objective optimization in the field of metabolic engineering when both continuous and integer decision variables are involved in the model. In particular, we propose a multi-objective model that may be used to suggest reaction deletions that...

Descripción completa

Detalles Bibliográficos
Autores principales: Andrade, Ricardo, Doostmohammadi, Mahdi, Santos, João L., Sagot, Marie-France, Mira, Nuno P., Vinga, Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041195/
https://www.ncbi.nlm.nih.gov/pubmed/32093622
http://dx.doi.org/10.1186/s12859-020-3377-1