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MOMO - multi-objective metabolic mixed integer optimization: application to yeast strain engineering
BACKGROUND: In this paper, we explore the concept of multi-objective optimization in the field of metabolic engineering when both continuous and integer decision variables are involved in the model. In particular, we propose a multi-objective model that may be used to suggest reaction deletions that...
Autores principales: | Andrade, Ricardo, Doostmohammadi, Mahdi, Santos, João L., Sagot, Marie-France, Mira, Nuno P., Vinga, Susana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041195/ https://www.ncbi.nlm.nih.gov/pubmed/32093622 http://dx.doi.org/10.1186/s12859-020-3377-1 |
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