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Systemic exosomal miR-193b-3p delivery attenuates neuroinflammation in early brain injury after subarachnoid hemorrhage in mice

BACKGROUND: Inflammation is a potential crucial factor in the pathogenesis of subarachnoid hemorrhage (SAH). Circulating microRNAs (miRNAs) are involved in the regulation of diverse aspects of neuronal dysfunction. The therapeutic potential of miRNAs has been demonstrated in several CNS disorders an...

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Detalles Bibliográficos
Autores principales: Lai, Niansheng, Wu, Degang, Liang, Tianyu, Pan, Pengjie, Yuan, Guiqiang, Li, Xiang, Li, Haiying, Shen, Haitao, Wang, Zhong, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041199/
https://www.ncbi.nlm.nih.gov/pubmed/32098619
http://dx.doi.org/10.1186/s12974-020-01745-0