An albumin-binding domain and targeting peptide-based recombinant protein and its enediyne-integrated analogue exhibit directional delivery and potent inhibitory activity on pancreatic cancer with K-ras mutation

Efficient enrichment and transmembrane transport of cytotoxic reagents are considered to be effective strategies to increase the efficiency and selectivity of antitumor drugs targeting solid tumors. In the present study, a recombinant protein ABD-LDP-Ec consisting of the albumin-binding domain (ABD)...

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Detalles Bibliográficos
Autores principales: Sheng, Weijin, Geng, Jing, Li, Liang, Shang, Yue, Jiang, Min, Zhen, Yongsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041235/
https://www.ncbi.nlm.nih.gov/pubmed/32020213
http://dx.doi.org/10.3892/or.2020.7468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041235/
https://www.ncbi.nlm.nih.gov/pubmed/32020213
http://dx.doi.org/10.3892/or.2020.7468

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