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Heterogeneous components of lung adenocarcinomas confer distinct EGFR mutation and PD-L1 expression
BACKGROUND: Lung adenocarcinoma (LAC) is composed of lepidic, papillary, mucinous, micropapillary and solid components in its parenchyma. Complex responses to therapeutics result from intratumoral heterogeneity. However, it remains confused that what components in a mixed LAC tumor are responsible t...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041262/ https://www.ncbi.nlm.nih.gov/pubmed/32093629 http://dx.doi.org/10.1186/s12885-020-6631-z |