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Heterogeneous components of lung adenocarcinomas confer distinct EGFR mutation and PD-L1 expression

BACKGROUND: Lung adenocarcinoma (LAC) is composed of lepidic, papillary, mucinous, micropapillary and solid components in its parenchyma. Complex responses to therapeutics result from intratumoral heterogeneity. However, it remains confused that what components in a mixed LAC tumor are responsible t...

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Detalles Bibliográficos
Autores principales: Cai, Yiran, Wu, Hongbo, Shi, Xiaoqin, Dong, Yujie, Chang, Xiujun, Zhang, Li, Zhou, Lijuan, Su, Dan, Yang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041262/
https://www.ncbi.nlm.nih.gov/pubmed/32093629
http://dx.doi.org/10.1186/s12885-020-6631-z