Cytosine methylation of mature microRNAs inhibits their functions and is associated with poor prognosis in glioblastoma multiforme

BACKGROUND: Literature reports that mature microRNA (miRNA) can be methylated at adenosine, guanosine and cytosine. However, the molecular mechanisms involved in cytosine methylation of miRNAs have not yet been fully elucidated. Here we investigated the biological role and underlying mechanism of cy...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheray, Mathilde, Etcheverry, Amandine, Jacques, Camille, Pacaud, Romain, Bougras-Cartron, Gwenola, Aubry, Marc, Denoual, Florent, Peterlongo, Pierre, Nadaradjane, Arulraj, Briand, Joséphine, Akcha, Farida, Heymann, Dominique, Vallette, François M., Mosser, Jean, Ory, Benjamin, Cartron, Pierre-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041276/
https://www.ncbi.nlm.nih.gov/pubmed/32098627
http://dx.doi.org/10.1186/s12943-020-01155-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041276/
https://www.ncbi.nlm.nih.gov/pubmed/32098627
http://dx.doi.org/10.1186/s12943-020-01155-z

Ejemplares similares