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Feasibility of intravitreal injections and ophthalmic safety assessment in marmoset (Callithrix jacchus) monkeys

To safeguard patients, regulatory authorities require that new drugs that are to be given by the intravitreal (IVT) route are assessed for their safety in a laboratory species using the same route of administration. Due to the high similarity of ocular morphology and physiology between humans and no...

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Detalles Bibliográficos
Autores principales: Korbmacher, Birgit, Atorf, Jenny, Fridrichs-Gromoll, Stephanie, Hill, Marilyn, Korte, Sven, Kremers, Jan, Mansfield, Keith, Mecklenburg, Lars, Pilling, Andrew, Wiederhold, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Copernicus GmbH 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041524/
https://www.ncbi.nlm.nih.gov/pubmed/32110696
http://dx.doi.org/10.5194/pb-4-93-2017