FOXC2 Promotes Oxaliplatin Resistance by Inducing Epithelial-Mesenchymal Transition via MAPK/ERK Signaling in Colorectal Cancer

BACKGROUND: Chemoresistance is a major obstacle to improving the survival rate of colorectal cancer (CRC) patients. Forkhead box protein C2 (FOXC2), a member of the forkhead box (Fox) transcription factor family, is reported to be an important regulator of epithelial-to-mesenchymal transition (EMT)...

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Detalles Bibliográficos
Autores principales: Chen, Yihong, Deng, Ganlu, Fu, Yaojie, Han, Ying, Guo, Cao, Yin, Ling, Cai, Changjing, Shen, Hong, Wu, Shaobin, Zeng, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041600/
https://www.ncbi.nlm.nih.gov/pubmed/32110058
http://dx.doi.org/10.2147/OTT.S241367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041600/
https://www.ncbi.nlm.nih.gov/pubmed/32110058
http://dx.doi.org/10.2147/OTT.S241367

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