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Multiple actin networks coordinate mechanotransduction at the immunological synapse

Activation of naive T cells by antigen-presenting cells (APCs) is an essential step in mounting an adaptive immune response. It is known that antigen recognition and T cell receptor (TCR) signaling depend on forces applied by the T cell actin cytoskeleton, but until recently, the underlying mechanis...

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Detalles Bibliográficos
Autores principales: Blumenthal, Daniel, Burkhardt, Janis K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041673/
https://www.ncbi.nlm.nih.gov/pubmed/31977034
http://dx.doi.org/10.1083/jcb.201911058