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GABA in, garbage out: AIS-located proteasomes regulate the developmental GABA switch

The GABA response switch from excitatory to inhibitory is a key event in neuronal maturation that depends on the regulated expression of chloride transporters NKCC1 and KCC2. In this issue, Lee et al. (2020. J. Cell. Biol. https://doi.org/10.1083/jcb.201903033) describe how degradation of NKCC1 by p...

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Detalles Bibliográficos
Autor principal: Leterrier, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041697/
https://www.ncbi.nlm.nih.gov/pubmed/31930378
http://dx.doi.org/10.1083/jcb.201912006