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GABA in, garbage out: AIS-located proteasomes regulate the developmental GABA switch
The GABA response switch from excitatory to inhibitory is a key event in neuronal maturation that depends on the regulated expression of chloride transporters NKCC1 and KCC2. In this issue, Lee et al. (2020. J. Cell. Biol. https://doi.org/10.1083/jcb.201903033) describe how degradation of NKCC1 by p...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Rockefeller University Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041697/ https://www.ncbi.nlm.nih.gov/pubmed/31930378 http://dx.doi.org/10.1083/jcb.201912006 |