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Glutamylation of deubiquitinase BAP1 controls self-renewal of hematopoietic stem cells and hematopoiesis

All hematopoietic lineages are derived from a limited pool of hematopoietic stem cells (HSCs). Although the mechanisms underlying HSC self-renewal have been extensively studied, little is known about the role of protein glutamylation and deglutamylation in hematopoiesis. Here, we show that carboxype...

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Detalles Bibliográficos
Autores principales: Xiong, Zhen, Xia, Pengyan, Zhu, Xiaoxiao, Geng, Jingjing, Wang, Shuo, Ye, Buqing, Qin, Xiwen, Qu, Yuan, He, Luyun, Fan, Dongdong, Du, Ying, Tian, Yong, Fan, Zusen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041701/
https://www.ncbi.nlm.nih.gov/pubmed/31699823
http://dx.doi.org/10.1084/jem.20190974