A super enhancer controls expression and chromatin architecture within the MHC class II locus

Super enhancers (SEs) play critical roles in cell type–specific gene regulation. The mechanisms by which such elements work are largely unknown. Two SEs termed DR/DQ-SE and XL9-SE are situated within the human MHC class II locus between the HLA-DRB1 and HLA-DQA1 genes and are highly enriched for dis...

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Detalles Bibliográficos
Autores principales: Majumder, Parimal, Lee, Joshua T., Rahmberg, Andrew R., Kumar, Gaurav, Mi, Tian, Scharer, Christopher D., Boss, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041702/
https://www.ncbi.nlm.nih.gov/pubmed/31753848
http://dx.doi.org/10.1084/jem.20190668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041702/
https://www.ncbi.nlm.nih.gov/pubmed/31753848
http://dx.doi.org/10.1084/jem.20190668

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