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Mapping and targeting of the leukemic microenvironment

Numerous studies support a role of the microenvironment in maintenance of the leukemic clone, as well as in treatment resistance. It is clear that disruption of the normal bone marrow microenvironment is sufficient to promote leukemic transformation and survival in both a cell autonomous and non–cel...

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Detalles Bibliográficos
Autores principales: Witkowski, Matthew T., Kousteni, Stavroula, Aifantis, Iannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041707/
https://www.ncbi.nlm.nih.gov/pubmed/31873722
http://dx.doi.org/10.1084/jem.20190589