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Human tau pathology transmits glial tau aggregates in the absence of neuronal tau

Tauopathies are characterized by abnormal accumulation of tau protein in neurons and glia. In Alzheimer’s disease (AD), tau aggregates in neurons, while in corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP), tau also aggregates in astrocytes and oligodendrocytes. We previously...

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Detalles Bibliográficos
Autores principales: Narasimhan, Sneha, Changolkar, Lakshmi, Riddle, Dawn M., Kats, Alexandra, Stieber, Anna, Weitzman, Sarah A., Zhang, Bin, Li, Zhiyong, Roberson, Erik D., Trojanowski, John Q., Lee, Virginia M.Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041709/
https://www.ncbi.nlm.nih.gov/pubmed/31826239
http://dx.doi.org/10.1084/jem.20190783