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Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses

Well-ordered HIV-1 envelope glycoprotein (Env) trimers are prioritized for clinical evaluation, and there is a need for an improved understanding about how elicited B cell responses evolve following immunization. To accomplish this, we prime-boosted rhesus macaques with clade C NFL trimers and ident...

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Detalles Bibliográficos
Autores principales: Phad, Ganesh E., Pushparaj, Pradeepa, Tran, Karen, Dubrovskaya, Viktoriya, Àdori, Monika, Martinez-Murillo, Paola, Vázquez Bernat, Néstor, Singh, Suruchi, Dionne, Gilman, O’Dell, Sijy, Bhullar, Komal, Narang, Sanjana, Sorini, Chiara, Villablanca, Eduardo J., Sundling, Christopher, Murrell, Benjamin, Mascola, John R., Shapiro, Lawrence, Pancera, Marie, Martin, Marcel, Corcoran, Martin, Wyatt, Richard T., Karlsson Hedestam, Gunilla B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041718/
https://www.ncbi.nlm.nih.gov/pubmed/31704807
http://dx.doi.org/10.1084/jem.20191155