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Sepsis induced cognitive impairments by disrupting hippocampal parvalbumin interneuron-mediated inhibitory network via a D4-receptor mechanism

Patients who suffer sepsis often develop cognitive impairments, yet the underlying mechanisms largely remain to be elucidated. Increasing evidence has suggested that parvalbumin (PV) interneurons are required for the synchronization of neural activities and higher brain processes, whereas its dysfun...

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Detalles Bibliográficos
Autores principales: Ji, Muhuo, Li, Shuming, Zhang, Ling, Gao, Yuzhu, Zeng, Qiuting, Mao, Minjie, Yang, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041733/
https://www.ncbi.nlm.nih.gov/pubmed/32019903
http://dx.doi.org/10.18632/aging.102755