PRMT5-TRIM21 interaction regulates the senescence of osteosarcoma cells by targeting the TXNIP/p21 axis

Osteosarcoma (OS) is the most common bone malignancy in adolescents and has poor clinical outcomes. Protein arginine methyltransferase 5 (PRMT5) has recently been shown to be aberrantly expressed in various cancers, yet its role in OS remains elusive. Here, we found that PRMT5 was overexpressed in O...

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Detalles Bibliográficos
Autores principales: Li, Yu-Hang, Tong, Kui-Leung, Lu, Jun-Lei, Lin, Jie-Bin, Li, Zhen-Yan, Sang, Yuan, Ghodbane, Abdelmoumin, Gao, Xue-Juan, Tam, Man-Seng, Hu, Chang-Deng, Zhang, Huan-Tian, Zha, Zhen-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041745/
https://www.ncbi.nlm.nih.gov/pubmed/32023548
http://dx.doi.org/10.18632/aging.102760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041745/
https://www.ncbi.nlm.nih.gov/pubmed/32023548
http://dx.doi.org/10.18632/aging.102760

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