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Dasatinib plus quercetin prevents uterine age-related dysfunction and fibrosis in mice

The uterine fibrosis contributes to gestational outcomes. Collagen deposition in the uterus is related to uterine aging. Senolytic therapies are an option for reducing health complications related to aging. We investigated effects of aging and the senolytic drug combination of dasatinib plus quercet...

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Detalles Bibliográficos
Autores principales: Cavalcante, Marcelo B., Saccon, Tatiana D., Nunes, Allancer D.C., Kirkland, James L., Tchkonia, Tamara, Schneider, Augusto, Masternak, Michal M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041753/
https://www.ncbi.nlm.nih.gov/pubmed/31955151
http://dx.doi.org/10.18632/aging.102772