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In vivo protective effect of adipsin-deficiency on spontaneous knee osteoarthritis in aging mice

The adipokine adipsin is an emerging mediator of human osteoarthritis (OA) progression. Here, we investigated its in vivo role in the development of spontaneous OA in aging mice. We compared articular knee joint morphology, histology in knee cartilage, synovial membrane, subchondral bone, meniscus,...

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Detalles Bibliográficos
Autores principales: Paré, Frédéric, Tardif, Ginette, Fahmi, Hassan, Ouhaddi, Yassine, Pelletier, Jean-Pierre, Martel-Pelletier, Johanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041762/
https://www.ncbi.nlm.nih.gov/pubmed/32012117
http://dx.doi.org/10.18632/aging.102784