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In vivo protective effect of adipsin-deficiency on spontaneous knee osteoarthritis in aging mice
The adipokine adipsin is an emerging mediator of human osteoarthritis (OA) progression. Here, we investigated its in vivo role in the development of spontaneous OA in aging mice. We compared articular knee joint morphology, histology in knee cartilage, synovial membrane, subchondral bone, meniscus,...
Autores principales: | Paré, Frédéric, Tardif, Ginette, Fahmi, Hassan, Ouhaddi, Yassine, Pelletier, Jean-Pierre, Martel-Pelletier, Johanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041762/ https://www.ncbi.nlm.nih.gov/pubmed/32012117 http://dx.doi.org/10.18632/aging.102784 |
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