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Evaluation of antiviral T cell responses and T(SCM) cells in volunteers enrolled in a phase I HIV-1 subtype C prophylactic vaccine trial in India

T cells play an important role in controlling viral replication during HIV infection. An effective vaccine should, therefore, lead to the induction of a strong and early viral-specific CD8(+) T cell response. While polyfunctional T cell responses are thought to be important contributors to the antiv...

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Detalles Bibliográficos
Autores principales: Munusamy Ponnan, Sivasankaran, Hayes, Peter, Fernandez, Natalia, Thiruvengadam, Kannan, Pattabiram, Sathyamurthi, Nesakumar, Manohar, Srinivasan, Ashokkumar, Kathirvel, Sujitha, Shankar, Janani, Goyal, Rajat, Singla, Nikhil, Mukherjee, Joyeeta, Chatrath, Shweta, Gilmour, Jill, Subramanyam, Sudha, Prasad Tripathy, Srikanth, Swaminathan, Soumya, Hanna, Luke Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041807/
https://www.ncbi.nlm.nih.gov/pubmed/32097435
http://dx.doi.org/10.1371/journal.pone.0229461