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Aberrant activation of bone marrow Ly6C (high) monocytes in diabetic mice contributes to impaired glucose tolerance

Accumulating evidence indicates that diabetes and obesity are associated with chronic low-grade inflammation and multiple organ failure. Tissue-infiltrated inflammatory M1 macrophages are aberrantly activated in these conditions and contribute to hyperglycemia and insulin resistance. However, it is...

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Detalles Bibliográficos
Autores principales: Ikeda, Yosuke, Sonoda, Noriyuki, Bachuluun, Battsetseg, Kimura, Shinichiro, Ogawa, Yoshihiro, Inoguchi, Toyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041861/
https://www.ncbi.nlm.nih.gov/pubmed/32097444
http://dx.doi.org/10.1371/journal.pone.0229401