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Quantification of fluorophore distribution and therapeutic response in matched in vivo and ex vivo pancreatic cancer model systems

Therapeutic resistance plagues cancer outcomes, challenging treatment particularly in aggressive disease. A unique method to decipher drug interactions with their targets and inform therapy is to employ fluorescence-based screening tools; however, to implement productive screening assays, adequate m...

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Detalles Bibliográficos
Autores principales: Solanki, Allison, King, Diana, Thibault, Guillaume, Wang, Lei, Gibbs, Summer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041865/
https://www.ncbi.nlm.nih.gov/pubmed/32097436
http://dx.doi.org/10.1371/journal.pone.0229407