Neurogranin stimulates Ca(2+)/calmodulin-dependent kinase II by suppressing calcineurin activity at specific calcium spike frequencies

Calmodulin sits at the center of molecular mechanisms underlying learning and memory. Its complex and sometimes opposite influences, mediated via the binding to various proteins, are yet to be fully understood. Calcium/calmodulin-dependent protein kinase II (CaMKII) and calcineurin (CaN) both bind o...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Lu, Lai, Massimo, Cole, Stephen, Le Novère, Nicolas, Edelstein, Stuart J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041932/
https://www.ncbi.nlm.nih.gov/pubmed/32049957
http://dx.doi.org/10.1371/journal.pcbi.1006991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041932/
https://www.ncbi.nlm.nih.gov/pubmed/32049957
http://dx.doi.org/10.1371/journal.pcbi.1006991

Ejemplares similares