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MAGE-A inhibit apoptosis and promote proliferation in multiple myeloma through regulation of BIM and p21(Cip1)

The type I Melanoma Antigen Gene (MAGE) A3 is a functional target associated with survival and proliferation in multiple myeloma (MM). To investigate the mechanisms of these oncogenic functions, we performed gene expression profiling (GEP) of p53 wild-type human myeloma cell lines (HMCL) after MAGE-...

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Detalles Bibliográficos
Autores principales: Mei, Anna Huo-Chang, Tung, Kaity, Han, Jessie, Perumal, Deepak, Laganà, Alessandro, Keats, Jonathan, Auclair, Daniel, Chari, Ajai, Jagannath, Sundar, Parekh, Samir, Cho, Hearn Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041939/
https://www.ncbi.nlm.nih.gov/pubmed/32133047
http://dx.doi.org/10.18632/oncotarget.27488