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Novel approaches leading towards peptide GPCR de‐orphanisation

The discovery of novel ligands for orphan GPCRs has profoundly affected our understanding of human biology, opening new opportunities for research, and ultimately for therapeutic development. Accordingly, much effort has been directed towards the remaining orphan receptors, yet the rate of GPCR de‐o...

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Detalles Bibliográficos
Autores principales: Hauser, Alexander S., Gloriam, David E., Bräuner‐Osborne, Hans, Foster, Simon R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042120/
https://www.ncbi.nlm.nih.gov/pubmed/31863461
http://dx.doi.org/10.1111/bph.14950